CBD & Magnesium - Comparison & Questions

As natural healers, CBD and magnesium share many health benefits including supporting overall wellness and tackling issues like insomnia and anxiety. However, they also offer differ in their potential benefits, meaning that one may be better suited to your needs than another.

Don’t be mistaken and think there is a battle between these two powerful products; CBD and magnesium can indeed be taken together, meaning you don’t need to necessarily choose one or the other. 

To best understand how CBD and magnesium can be used together, let’s first explore how each one works on its own.

How CBD interacts with the body

The endocannabinoid system, or ECS, helps regulate many vital processes in the body such as sleep, mood, metabolism, and recognition of pain. CBD interacts with your ECS by targeting numerous receptors in the brain and major biological systems, producing desired results like pain reduction and a more balanced mood. 

The health benefits of CBD are too numerous to list, but one of the most sought-after properties is its inflammation-fighting power. CBD can lessen undesirable immune responses while positively impacting overall health.  

Moreover, CBD is believed to benefit serotonin levels, helping to keep anxiety in check.

How magnesium interacts with the body

Magnesium is an essential mineral that is vital in more than 300 crucial bodily functions. From heart health and blood pressure regulation to muscle and nerve function, and blood glucose control, magnesium plays a crucial role for your brain and body.  

Here’s an interesting fact – your body cannot create magnesium. This mineral must be absorbed through the foods you eat and supplements you take. Once absorbed, your body uses magnesium for the process of converting food into energy, among many other important roles. 

A magnesium deficiency, also called hypomagnesemia, can lead to several serious physical and mental health problems. Symptoms of magnesium deficiency are often overlooked or misdiagnosed, so it’s valuable to take the time to understand what they are. 

Lacking this valuable mineral can lower your calcium, weakening bones and osteoporosis. Symptoms such as muscle tremors, cramps, and twitching are also signs that your body is in dire need of magnesium. 

Magnesium is also tied to mental health, as a lack of magnesium can cause feelings of apathy, delirium, and anxiety.

CBD vs. Magnesium - How Benefits Overlap 

Both CBD and magnesium can boost moods and alleviate anxiety

CBD and magnesium are a powerful stress-busting duo worth checking out if you experience chronic anxiety. If you are living in a constant state of fight or flight, your body is burning through magnesium stores at an abnormally high rate. This becomes a double-edged sword because anxiety depletes magnesium AND depleted magnesium levels can make you feel more anxious. Adding magnesium can not only boost your mood but joining CBD into the mix can positively affect the serotonin levels in your brain which can also help alleviate anxiety.

A large percentage of people who take CBD use it to treat anxiety. CBD can produce similar results to magnesium in terms of boosting your mood and decreasing anxious emotions, making these nutrients a perfect combo. The best product to use for attaining these relaxing effects is CBD oil because of its bioavailability, or absorption rate. An even better option is packing a punch with both CBD and magnesium. 

Both CBD and magnesium can help with achieving healthy sleep

CBD and magnesium are a powerful pair because they both target your body’s homeostatic response… aka keeping your body and brain in balance. While CBD interacts with the endocannabinoid system which helps regulate your circadian rhythm and sleep cycle, magnesium supports this process by directly lowering cortisol levels and inducing muscle relaxation. 

When your muscles relax, your body can move into a parasympathetic, or rest and digest state, which is ideal for bedtime. Magnesium has also been shown to relax the central nervous system, thus relaxing not only your body but also your mind. CBD helps control cortisol levels, thus also encouraging sleepiness. 

The combination of CBD oil and magnesium before bedtime can be a powerful yet natural remedy for sleeplessness. This dynamic duo has been shown to relieve insomnia, improve the length and quality of sleep, and lessen the time it takes to fall asleep. 

Both CBD and magnesium can assist with circulatory health

Magnesium is an essential mineral that contributes to a wide array of heart-supporting benefits, such as contributing to relaxing blood vessels and helping maintain healthy blood pressure. This pertinent mineral has also been proven to decrease the risk of having a stroke, coronary heart disease, hypertension, and other metabolic disorders.

CBD’s anti-inflammatory properties may potentially reduce risk factors leading to heart disease, like high blood pressure just like its companion magnesium. In addition, the antioxidant properties of CBD can lead to healthier overall cardiac function. 

Keep in mind that CBD can affect current medications such as some high blood pressure prescriptions. If you are considering using CBD for circulatory health, seek advice from your doctor first. 

Both CBD and magnesium can alleviate headaches

Two of the top natural treatments for headaches are CBD and magnesium. When these are combined, they pack a powerful punch. A common cause for headaches is a lack of magnesium, so adding supplements or food that is rich in this mineral to your diet can immediately reduce the onset of reoccurring headaches. 

CBD is also an effective treatment for migraines and other types of headaches such as cluster headaches and hangovers. Plus, in addition to headache help, CBD may also reduce symptoms associated with headaches such as nausea, vomiting, and sleep issues.

Both CBD and magnesium can help relieve arthritis pain

Millions of people are afflicted with joint or arthritis pain, but luckily, magnesium and CBD can help. Due to its anti-inflammatory properties, CBD activates endocannabinoid receptors in the body, decreasing cytokine production and immune cell mobilization. In other words, it helps reduce pain associated with arthritis. 

The anti-oxidative properties of magnesium impact the body in a very similar way as CBD by helping to prevent the release of inflammatory responses from the body which impact joint pain. Proper magnesium intake also promotes the absorption of calcium, which is necessary for bone and joint health over time.

It is easy to see that taking magnesium and CBD together can positively impact many health issues. From sleep to pain, this powerful combo can be used for one-time situations or more ideally on a regular basis for improved overall health. 

Use CBD and Magnesium Side-by-Side 

Botanika Life offers various potent CBD products that address everything from insomnia to aches and pains. With a host of natural ingredients, Serentika CBD Sleep Spray utilizes magnesium, GABA, broad-spectrum CBD, and melatonin to melt away your stress and induce sleep. The end result is a natural sleep aid that won’t cause any intoxication, hangovers, or physical dependency. 




With the highest quality natural ingredients, Botanika Life utilizes organic CBD and the power of organic plants to bring you clean and effective products. Backed by third-party verification, rest assured that what you put on and in your body is sustainable, vegan, and free of chemicals or pesticides. 



By Emily Wegener

With a unique background as an Integrative Nutrition Health Coach, Masters Degree in Teaching and experience in Psychology, Emily spends much of her time researching and trying out new holistic healing modalities.